Can you treat psoriasis with lion’s mane mushrooms?

The Lion’s mane mushroom can fight psoriasisbringing hope for those suffering from this skin condition.

Let’s delve into the fascinating world of lion’s mane mushroom and explore its potential benefits for people struggling with psoriasis.

Discover how the remarkable properties of this mushroom could provide relief and support on your skin health journey.

What is psoriasis?

How can lion’s mane help psoriasis?

Is lion’s mane good for skin?

Is lion’s mane good for inflammation?

What are all the benefits of lion’s mane?

Who Shouldn’t Use Lion’s Mane?

How can you take lion’s mane for psoriasis?

What is the ideal dosage of lion’s mane for psoriasis?

How much lion’s mane is in AdaptogenShroomsgranola?

To learn more about this incredible adaptogenic fungus, read our guide to lion’s mane mushrooms.

What is a lion’s mane?

Lion’s mane is an adaptogenic mushroom and one of the the healthiest mushrooms you can eat. It is commonly grown in North America, Northern Asia and Northern Europe and is widely used in alternative medicine for its beneficial effects on mental, physical and spiritual health.

Learn more about how this mushroom works our guide to adaptogenic mushrooms.

What is psoriasis?

Psoriasis is a chronic autoimmune condition that affects the skin, causing skin cells to build up rapidly. This leads to the formation of thick, red patches covered with silvery scales. Psoriasis is not contagious and can vary in severity from mild to severe. While the exact cause is unknown, it is believed to involve a combination of genetic and environmental factors.

Symptoms of psoriasis include:

  • red patches of skin covered with thick, silvery scales
  • dry, cracked skin that may bleed;
  • itching or burning sensation in the affected areas
  • swollen and stiff joints (psoriatic arthritis)
  • pitted or ridged nails
  • thickened, inflamed areas of skin (plaque psoriasis)
  • small patches of scaling (intestinal psoriasis)
  • smooth, red patches on body folds (inverse psoriasis)
  • scaling or crusting of the scalp (scalp psoriasis)
  • changes in the nails, such as discoloration or separation from the nail bed;

Lion’s Mane and Psoriasis—A Look at Lion’s Mane Mushroom Clinical Studies

While there isn’t a lot of research on lion’s mane and psoriasis specifically, we do know that lion’s mane can have anti-inflammatory effects. Since psoriasis is an autoimmune disease—and autoimmune disorders involve out-of-control inflammation in the body—it’s not too far-fetched to assume that lion’s mane just might slow down psoriasis and relieve its symptoms.

In addition, lion’s mane appears to stimulate nerve growth and provide pain relief. These properties can potentially improve the quality of life for those with psoriasis.

Lion’s Rock, Neurogenesisand Psoriasis

According to a recent studyThefruits oflion’s mane mushrooms contain compounds whichstimulate growth of the newnerve cells by promoting the production ofnerve growth factors (NGF). This study states that “ericenones and erinacins isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells.

ONE Study 2023 found that the lion’s mane mushrooms “had a significant impact on his growthbrain cells and improved memory formation,” confirming that these mushrooms help with memorygrowth stimulation of nerve cells.

ForMore information in this amazing benefit of the lion’s mane, read our guide to lion’s mane and neurogenesis. Now, let’s look at why neurogenesis is beneficial for people with psoriasis.

ONE study on the connection between neural cells, immunity and skin diseases found that “NGF is increasingly recognized as a potent immunomodulator, promoting cross-talk between neuronal cells, glia and immune cells and facilitating monocyte/macrophage migration across the vascular endothelium”.

Through its effects as an immunomodulator, NGF could alleviate the symptoms of psoriasis, but more research is needed in humans to understand this benefit.

Is lion’s mane good for skin?

Lion’s mane is anecdotally used for healingskin diseasessuch asskin rashespsoriasis and eczema, and is an ingredient often found inskin care. However, so far there is nonemedically tested research on the topic of lion’s mane and skin care.

Lion’s mane has well-researched anti-inflammatory andantioxidant propertieswhich will definitely help with healthy skin, especially if your skin is prone to breakouts and rashes (a common symptom of psoriasis and eczema).

Does lion’s mane help with inflammation?

The lion’s mane is fullpowerful antioxidants, andresearch suggests that it could relieve both acute andchronic inflammation associated with psoriasis andpsoriatic ARTHRITIS.

Theanti-inflammatory and antioxidant properties of the lion’s mane were investigated in a Animal study 2014. This study found that water-soluble oligosaccharides found in lion’s mane were potentantioxidant activities.

Other studypublished in 2022, found that two compounds found in lion’s mane helpedreducing inflammation:

The four standard aromatic compounds were evaluated for their inhibitory effects on the secretion of TNF-α, IL-6 and NO, three major pro-inflammatory mediators, in the RAW 264.7 macrophage model. Two of them showed moderate inhibitory effects indicating their potential anti-inflammatory activity, which may provide the basis for the traditional medicinal use of H. erincacus.

To learn more about how the lion’s manereduces inflammation and oxidative stressCheckout our article on the anti-inflammatory benefits of lion’s mane mushrooms.

Can Lion’s Mane Relieve Pain and Repair Nerves?

According to research, lion’s mane can reduce nerve pain and helpnervous system injury recovery. One animal study looked at the effects of the lion’s mane on the nervedamage caused from crush injury in rats. This study concluded that “H. Fresh erinaceus fruiting bodies could promote the regeneration of injured rat peroneal nerve in the early stage of recovery.’

Other study examined the effects of Hericium erinaceus on nerve pain. The researchers gave the animals cisplatin, an anticancer drug that can cause cisplatin-induced peripheral neuropathy (CIPN). This study concluded that “Hericium erinaceus showed therapeutic effects in a murine model of peripheral neuropathy” and added that “it may be an effective and safe therapeutic agent used in peripheral neuropathy.”

For more information on taking lion’s mane for pain relief, read our article on lion’s mane and neuropathy.

Possible benefits of lion’s mane mushrooms

Lion's mane supports gut health

From the mind to the heart and everything in between, lion’s mane seems to benefit every part of the human body. According to the latest research, the lion’s mane mushroom:

  • improvedmental health and reduced symptoms ofanxiety and depression by regulating the production of neurotransmitters that play a role in mood regulation
  • was helped toweight management and are promotedweight loss increasing the body’s metabolism and reducing appetite
  • inhibited the growth of cancer cells in laboratory studies, with its effects onBreast cancer and leukemia is particularly beneficial
  • are protected fromheart disease lowering cholesterol levels and improving blood circulation
  • supportedgut health increasing the number of beneficial bacteria in the gut, which can also help patients with digestive conditions such asCrohn’s disease and IBS
  • balancedblood sugar levels increasing the body’s sensitivity to insulin
  • reduced the symptoms of chronic diseases, such asmultiple sclerosisreducing inflammation and improving nerve function
  • are protectedbrain health andimproved cognitive impairments caused by conditions such asAlzheimer’s disease and dementia
  • strengthen itimmune system increasing the production of white blood cells

If we were to list every benefit of lion’s mane, we would be here all day. Instead, check out our guide topotential health benefits of lion’s mane mushrooms to learn more about this topic.

Contraindications for lion’s mane

Lion’s mane is safe for most people. However, there are some contraindications to taking lion’s mane mushrooms. If you have allergies to mold, yeast, or other fungi, be careful when you start taking lion’s mane.

People taking medication for surehealth conditionssuch as diabetes and blood clotting, you may want toavoid the lion’s mane until they discuss itsafety and side effects taking this mushroom with their medication with a doctor.

To learn more about whether you should get the lion’s mane, read on Our blog post on lion’s mane contraindications.

Interested in taking lion’s mane for psoriasis?

If you want to take lion’s mane for psoriasis, why not try our medicinal mushroom granola? Our delicious medicated granola is vegan, gluten-free, made with high-quality organic ingredients and contains a super-concentrated lion’s mane extract.

And, if you want more adaptive mushroom goodness, we have that too turkey tail mushroom extractwhich has also been shown to help relieve inflammation and provide benefits for optimal health. Learn more about the benefits of turkey tail here.

How Much Lion’s Mane Should You Take for Psoriasis?

Due to a lack of research, we do not yet know the optimal dosage of lion’s mane for psoriasis. If you are new to this mushroom, it is best to start low and work your way up to higher doses as you get used to the effects of this mushroom. For more information, check out our lion’s mane dosage guide.

How much lion’s mane is in AdaptogenShroomsGranola?

AdaptogenShroomsgranola uses high qualitylion’s mane extractsmade from wholemedicinal mushrooms. Our double extraction method extracts both water-soluble beta-glucans and alcohol-soluble triterpenes. Our brewing process breaks down the indigestible chitin cell walls of the mushroom to extract far more of these compounds than conventional processes.

 AdaptogenShroomsfunctional granola

One serving of granola provides us with 250 mg of super-concentratelion’s mane mushroom extractwhich is eight times more concentrated than normallion’s mane supplements. So you get as much potency in lion’s mane as you would if you took a 2000 mglion’s mane powderall in a granola bowl.

Frequently asked questions about lion’s mane and psoriasis

What are the negative effects of lion’s mane?

Available research and centuries of usethey suggest that lion’s mane has few negative effects. People new to adaptogenic mushrooms may experience mild digestive distress when they start taking lion’s mane, but these side effects should subside within a few days of regular use. To learn more about this topic, head over to Our blog post on lion’s mane side effects.

Is it safe to take lion’s mane daily?

Yes, it is safe to take lion’s mane daily, even in high doses. Taking this medicinal mushroom regularly will make its long-term benefits more apparent and help yougeneral health and well-being.

Does Lion’s Mane Affect Estrogen?

Due to the limited research on the subject of lion’s mane andwomen’s health, there is no conclusive evidence for the effects of lion’s mane on estrogen. However, this mushroom appears to stabilize hormone production, at least in animals, which warrants further research into its effects on human hormone production.

Is Lion’s Mane addictive?

No, lion’s mane is not addictive, even when taken in high doses. Lion’s mane does not contain psilocybin, a compound that causes a “high” in psychedelic mushrooms. We explain for the lion’s mane will not carry you high here.

What is the best mushroom for acne?

Some of the best mushrooms for acne are reishi, chaga, lion’s mane and Cordyceps mushrooms. We’re taking a deep dive the benefits of lion’s mane for acne in a recent blog post; Check it out.

Does lion’s mane increase testosterone?

This is one of the mostcommon questions We are asked by our customers and the answer is that while it does not increase testosterone per se, lion’s mane can stabilize testosterone production. We explain this process in depth our article on lion’s mane and testosterone. And forRelated topics, check out our blog post on lion’s mane and DHT.

Does Lion’s Mane Help Hair Growth?

Lion’s mane can help with hair growth and even prevent hair loss. Learn more about this benefit at Our blog post on lion’s mane and hair growth.

What are thethe lion’s mane spiritual benefits?

Because ofhealing effects of lion’s mane under conditions such asdepression and anxiety, many believe that the lion’s mane has spiritual benefits. Shaolin monks in ancient China used this mushroom in their daily practice as a way to improve concentration. It was believed to increase ‘Chi’, a mystical, energetic life force. Checkout Our blog post on the spiritual benefits of lion’s mane For more information.

What should I look for in alion mushroom supplement?

Here are some things to look out for when buyinglion’s mane mushroom powders and other lion’s mane supplements:

  • Look for a product that is certified organic or non-GMO (all AdaptogenShroomsproducts are certified organic and contain no GMO ingredients)
  • Make sure the product has been thoroughly tested by a third-party lab (as we have)
  • Make sure the lion’s mane extract or powder they use is strong (we use the strongest lion’s mane extract made with a double extraction process)

I can get the lion’s mane with othersfunctional mushrooms?

Yes, you can get the lion’s mane with any operating systemtypes of mushroomsincluding turkey tail mushrooms,shiitake mushroomsandmaitake mushrooms. When it comes to medicinal mushrooms, the whole is better than the sum of its parts.

It is the lion’s maneMushroom cultivation hard process?

The process of growing lion’s mane mushroom can be relatively simple using aorganic mushroom cultivation kit. These kits provide the necessary materials and instructions for cultivationfresh lion’s mane mushrooms at home.

And, if you wanthealthy diet without the obligations associated withgrowing your lion’s maneour granola is one way to ensure you enjoy the benefits of this mushroom in a quick, easy and delicious way.


  1. Lai, PL (2013). Its neurotrophic propertiesMedicinal lion’s mane mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International Journal of Medicinal Mushrooms15(6), 539–554.
  2. Martínez‐Mármol, R. (2023). Hericerin derivatives activate a pan-neurotrophic pathway in central hippocampal neurons that converges on ERK1/2 signaling that enhances spatial memory. Journal of Neurochemistry.
  3. Arck, PC (2006). Neuroimmunology of stress: The skin takes center stage. Journal of Investigative Dermatology, 126(8), 1697–1704.
  4. Hou, Y. (2015). Composition and antioxidant activity of water-soluble oligosaccharides from Hericium erinaceus. Molecular medicine reports, 11(5), 3794-3799.
  5. Xie, G. (2022). Secondary metabolites from Hericium erinaceus and their anti-inflammatory actions. Molecules (Basel, Switzerland), 27(7), 2157.
  6. Wong, KH (2011). Peripheral nerve regeneration after rat peroneal nerve crush injury by aqueous extract of medicinal mushroom Hericium erinaceus (Bul.: Fr) Pers. (Aphyllophoromycetideae). Evidence-based complementary and alternative medicine: eCAM, 2011, 580752.
  7. Ramazan, U. (2019) Therapeutic effect of Hericium erinaceus in an experimental model of peripheral neuropathy. Anatomy: International Journal of Experimental & Clinical Anatomy. Supplement 2019, Vol. 13 Issue S1, pS37-S37. 1/3 p.

Disclaimer Forij

The information provided in this article is not intended to diagnose, treat or cure any disease or illness and should not be taken asmedical advice. The statements contained herein have not been evaluated byFood and Drug Administration (FDA). Before adding lion’s mane to your health and wellness routine, talk to a healthcare professional about the potential benefits, side effects and uses of this mushroom.

Leave a comment